Suppressed Fluctuation in The GABAergic Signaling: Mathematical Modelling of The Neurotransmitter

The chemistry of the gamma aminobutyric acid (GABA) had been established. However, the explanation on the interplay between GABA receptors antagonize fundamental concept of the GABAergic Signaling‎. For example, glutamate spillover from excitatory afferent terminals leads to the modulation of GABAergic signals. However, this result is true with respect to GABAB receptors only. The physics of its interplay between the GABA receptors was theoretically investigated using the magnetic resonance imaging (MRI) because the proton gradient controls the intermediate energy storage for heat production and flagellar rotation. The MRI investigation of the GABAergic Signaling‎ is not a new concept in medicine. Molecular potential in the receptors increases the peak radiofrequency (RF) field (B1) amplitude and the holding potential of the GABA receptors. The suppressed fluctuation of the GABAergic Signaling‎ was noticed where the receptors are all actively involved in the GABAergic network. Hence, a dual technique was suggested to detect the suppressed GABAergic state in the human body.